Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2741569 | 0.96 | APEX1 (0.41) | PTGES2PDE3BPDE3AAPEX1GRM2 | |
| SCHEMBL91817 | 0.89 | PDE3B (0.43) | PTGES2PDE3BPDE3AGRM2PTGS2 | |
| SCHEMBL14206977 | 0.89 | PTGES2 (0.46) | PTGES2PDE3BPDE3AAPEX1PTGS2 | |
| SCHEMBL803426 | 0.88 | PDE3B (0.48) | PDE3BPDE3AAPPAKR1C3AKR1C2 | |
| SCHEMBL4567632 | 0.86 | PDE3B (0.47) | PDE3BPDE3AAPPAKR1C3AKR1C2 | |
| SCHEMBL12889477 | 0.86 | NFE2L2 (0.47) | PDE3BPDE3AAKR1C3AKR1C2PTGS2 | |
| SCHEMBL12826296 | 0.86 | NFE2L2 (0.47) | PDE3BPDE3AAKR1C3AKR1C2PTGS2 | |
| SCHEMBL13417748 | 0.86 | PTGES2 (0.43) | PTGES2PDE3BPDE3AAPEX1GRM2 | |
| SCHEMBL13967517 | 0.86 | PTGS2 (0.46) | PDE3BPDE3AAPPAKR1C3AKR1C2 | |
| SCHEMBL12696815 | 0.85 | PSEN1 (0.44) | PDE3BPDE3APSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 601 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043782-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-12043781-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-12043782-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| WO-2024017812-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2024-01-25 | — | — | WO | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-20230383186-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-30 | — | — | US | disclosed |
| US-20230383186-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-30 | — | — | US | disclosed |
| US-20080199635-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080167482-A1 | mesogenic group is linked to the C-atom No. 5 of the 1,3-dioxane-5-yl group; media showing a blue phase and their use in electro-optical light modulation elements | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| US-7390538-B2 | Liquid-crystal medium containing monofluoroterphenyl compounds | MERCK PATENT GMBH (DE) | 2008-06-24 | — | — | US | disclosed |
| US-20080116419-A1 | Mesogenic Compounds, Liquid Crystal Medium and Liquid Crystal Display | MERCK PATENT GMBH (DE) | 2008-05-22 | — | — | US | disclosed |
| US-20080083904-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-04-10 | — | — | US | disclosed |
| US-20070237907-A1 | PHOTOSTABLE LIQUID-CRYSTALLINE MEDIUM | MANABE ATSUTAKA | 2007-10-11 | — | — | US | disclosed |
| US-20070176146-A1 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070170395-A1 | Liquid crystal medium | MERCK PATENT GESELLSCHAFT | 2007-07-26 | — | — | US | disclosed |
| US-7211302-B2 | Photostable liquid crystalline medium | MERCK PATENT GMBH (DE) | 2007-05-01 | — | — | US | disclosed |
| US-20070001149-A1 | Liquid-crystal medium containing monofluoroterphenyl compounds | MERCK PATENT GMBH (DE) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | PTGES2 4478/4885PDE3B 3262/4885PDE3A 3309/4885 |
| US-20080083904-A1 | LIQUID-CRYSTALLINE MEDIUM | NEFM, OSBP, ALPG | PTGES2 3242/4885PDE3B 786/4885PDE3A 1198/4885 |
| US-20080116419-A1 | Mesogenic Compounds, Liquid Crystal Medium and Liquid Crystal Display | CRY1, CRY2, IK | PTGES2 1878/4885PDE3B 1399/4885PDE3A 1918/4885 |
| US-20080199635-A1 | LIQUID-CRYSTALLINE MEDIUM | L1CAM, NEFM, CHRM1 | PTGES2 3946/4885PDE3B 1953/4885PDE3A 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.