SCHEMBL919655

SCHEMBL919655

Cc1cccc(C)c1Oc1ccc(CNC(=O)c2cccnc2N)cc1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.52
HPGD P15428 4/20 0.51
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
PIK3CD O00329 1/20 0.50
POLB P06746 1/20 0.48
MAPK1 P28482 1/20 0.48
EGLN1 Q9GZT9 1/20 0.47
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPK14 Q16539 1/20 0.46
NSD2 O96028 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921191 0.91 MAPK8 (0.50) MAPK8HPGDLMNASMN1; SMN2PIK3CD
SCHEMBL921006 0.91 HPGD (0.51) MAPK8HPGDLMNASMN1; SMN2POLB
SCHEMBL919966 0.88 MAPK14 (0.61) MAPK8HPGDLMNASMN1; SMN2PIK3CD
SCHEMBL922484 0.87 HPGD (0.62) MAPK8HPGDLMNASMN1; SMN2POLB
SCHEMBL921056 0.86 LMNA (0.57) MAPK8HPGDLMNASMN1; SMN2PIK3CD
SCHEMBL921037 0.85 HPGD (0.66) MAPK8HPGDLMNASMN1; SMN2POLB
SCHEMBL920473 0.85 HPGD (0.57) MAPK8HPGDLMNASMN1; SMN2POLB
SCHEMBL920461 0.85 MAPK8 (0.67) MAPK8HPGDLMNASMN1; SMN2MEN1
SCHEMBL920714 0.85 MAPK8 (0.53) MAPK8HPGDLMNASMN1; SMN2POLB
SCHEMBL922349 0.84 HPGD (0.53) MAPK8HPGDLMNASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK8 2313/4885HPGD 1273/4885LMNA 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.