Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632774 | 0.85 | MAPK1 (0.41) | CYP2D6MAPK1AKR1C3AKR1C2TRPA1 | |
| SCHEMBL27952976 | 0.82 | TRPA1 (0.42) | MAPK1KMT2AAKR1C3AKR1C2TRPA1 | |
| SCHEMBL28806591 | 0.80 | NPC1 (0.41) | MAPK1AKR1C3AKR1C2TRPA1LMNA | |
| SCHEMBL10506289 | 0.79 | ADRA2A (0.65) | ADRA2AADRA1ACYP2D6MAPK1BLM | |
| SCHEMBL9735383 | 0.77 | CYP1A2 (0.43) | CYP2D6MAPK1AKR1C3AKR1C2TRPA1 | |
| SCHEMBL9197147 | 0.77 | ADRA2A (0.48) | ADRA2AADRA1ACYP2D6MAPK1BLM | |
| SCHEMBL16959886 | 0.74 | ALDH1A1 (0.40) | MAPK1AKR1C3AKR1C2TRPA1LMNA | |
| SCHEMBL9461082 | 0.73 | TRPA1 (0.55) | ADRA1ACYP2D6MAPK1BLMKMT2A | |
| SCHEMBL14185860 | 0.72 | KDM4E (0.57) | ADRA2AADRA1AMAPK1BLMKMT2A | |
| SCHEMBL835214 | 0.72 | KDM4E (0.57) | ADRA2AADRA1AMAPK1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485069-B1 | Process for producing optically active amines | SUMITOMO CHEMICAL CO (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-5200561-A | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5145998-A | Reduction of oxime or silyloxime | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0237305-B1 | A METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0485069-A1 | Process for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0237305-A2 | A method for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-16 | — | — | EP | disclosed |