SCHEMBL919861

SCHEMBL919861

CCCc1ccc(Oc2cc[c]cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
ACACB O00763 1/20 0.43
ACACA Q13085 1/20 0.43
ALDH1A1 P00352 2/20 0.43
RAB9A P51151 1/20 0.43
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
FFAR1 O14842 1/20 0.38
KMT2A Q03164 2/20 0.37
PLA2G1B P04054 1/20 0.37
ATG4B Q9Y4P1 1/20 0.37
LTA4H P09960 1/20 0.37
CA2 P00918 1/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
XBP1 P17861 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921443 0.89 LTA4H (0.43) THRBALDH1A1KMT2ALTA4HCA2
SCHEMBL2202805 0.87 THRB (0.52) THRBACACBACACAALDH1A1RAB9A
SCHEMBL9011773 0.85 ESR1 (0.50) THRBALDH1A1LPLLIPGKMT2A
SCHEMBL919737 0.83 SMN1; SMN2 (0.41) ALDH1A1RAB9ALPLLIPGLTA4H
SCHEMBL27629737 0.81 LPL (0.46) THRBALDH1A1LPLLIPGCA2
SCHEMBL920416 0.80 FFAR1 (0.40) THRBACACBACACAALDH1A1RAB9A
SCHEMBL17731 0.80
SCHEMBL28257690 0.80 TAAR1 (0.44) CA2
SCHEMBL427538 0.79 LTA4H (0.59) FFAR1LTA4H
SCHEMBL10027325 0.79 TEAD4 (0.50) THRBACACBACACAALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 THRB 1345/4885ACACB 2640/4885ACACA 2109/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 THRB 2399/4885ACACB 4147/4885ACACA 4016/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.