SCHEMBL921443

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9011773	0.93	ESR1 (0.50)	ALDH1A1HSD17B10THRBSMN1; SMN2LMNA
	SCHEMBL919861	0.89	THRB (0.43)	LTA4HCA2ALDH1A1HSD17B10THRB
	SCHEMBL145761	0.88	LTA4H (0.52)	LTA4HCA2CA1S1PR1S1PR3
	SCHEMBL579944	0.82	SIGMAR1 (0.55)	LTA4HS1PR1S1PR3ALDH1A1SMN1; SMN2
	SCHEMBL16933886	0.82	RARB (0.55)	LTA4HCA2CA1S1PR1S1PR3
	SCHEMBL8560021	0.82	HRH3 (0.50)	LTA4HALDH1A1HSD17B10LMNAESR1
	SCHEMBL475118	0.82	ALDH1A1 (0.57)	LTA4HALDH1A1HSD17B10THRBSMN1; SMN2
	SCHEMBL17930	0.82	CA2 (0.48)	CA2CA1ALDH1A1HPGDHSD17B10
	Water SCHEMBL28265892	0.82	CA2 (0.48)	CA2CA1ALDH1A1HPGDHSD17B10
	SCHEMBL8564624	0.82	LTA4H (0.45)	LTA4HCA2CA1S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.