Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199383 | 0.92 | HPGD (0.47) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9196782 | 0.87 | MAPT (0.38) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9205543 | 0.86 | ALDH1A1 (0.39) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9196940 | 0.85 | RAB9A (0.56) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9207049 | 0.81 | GAA (0.36) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9198647 | 0.80 | ACHE (0.37) | KMT2AHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9199236 | 0.80 | MAPT (0.39) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL9150595 | 0.75 | KDM4C (0.57) | MEN1KMT2AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL9199834 | 0.73 | GPR35 (0.38) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9202904 | 0.72 | ALDH1A1 (0.46) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |