Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 10/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 2/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.33 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199366 | 0.84 | TLR2 (0.33) | — | |
| SCHEMBL8126777 | 0.81 | PADI6 (0.48) | NPY1RPADI6PADI4 | |
| SCHEMBL8122653 | 0.80 | PADI6 (0.42) | PADI6PADI4 | |
| SCHEMBL9284142 | 0.80 | PADI6 (0.42) | PADI6PADI4 | |
| SCHEMBL9285714 | 0.80 | NPY1R (0.54) | NPY1RNPY5RNPY2RNPY4RNPFFR1 | |
| SCHEMBL8112793 | 0.80 | NPY1R (0.54) | NPY1RNPY5RNPY2RNPY4RNPFFR1 | |
| SCHEMBL8115106 | 0.80 | CA2 (0.44) | CA1CA2NPY1R | |
| SCHEMBL8126577 | 0.79 | NPY1R (0.44) | NPY1RNPY5RNPY2RPADI6NPY4R | |
| SCHEMBL9280771 | 0.79 | NPY1R (0.44) | NPY1RNPY5RNPY2RPADI6NPY4R | |
| SCHEMBL8112071 | 0.79 | MMP2 (0.39) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |