Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197681 | 0.89 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL9192909 | 0.80 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9193782 | 0.79 | AGT (0.41) | AGTR1AGTR2 | |
| SCHEMBL9047816 | 0.76 | CRHBP (0.47) | ACHECRHBPCRHR2AGTR1 | |
| SCHEMBL7299228 | 0.75 | AGTR1 (0.67) | ACHEAGTR1AGTR2 | |
| SCHEMBL9427847 | 0.75 | ACHE (0.48) | ACHECRHBPCRHR2 | |
| SCHEMBL7435257 | 0.74 | ACHE (0.54) | ACHEAGTR1AGTR2 | |
| SCHEMBL7907344 | 0.73 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL7308001 | 0.73 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL1258896 | 0.73 | ACHE (0.51) | ACHEAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445811-B1 | Nitrogen-containing heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-06-14 | — | — | EP | disclosed |
| US-5304565-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0445811-A2 | Nitrogen-containing heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-09-11 | — | — | EP | disclosed |