SCHEMBL919975

SCHEMBL919975

NCc1cccc(Oc2ccccc2C(F)(F)F)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 1/20 0.51
MAOB P27338 2/20 0.47
LOX P28300 1/20 0.45
LOXL2 Q9Y4K0 1/20 0.45
F10 P00742 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.43
LTA4H P09960 1/20 0.42
PTGS2 P35354 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
LPAR1 Q92633 1/20 0.40
LPAR5 Q9H1C0 1/20 0.40
PPARG P37231 2/20 0.40
DPP4 P27487 1/20 0.40
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
PLG P00747 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL923193 0.86 MAOB (0.57) FDFT1MAOBLOXLOXL2MRGPRX4
SCHEMBL5543329 0.85 FDFT1 (0.51) FDFT1MRGPRX4LTA4HPTGS2MEN1
SCHEMBL12238995 0.80 LOXL2 (0.46) MAOBLOXLOXL2LPAR1LPAR5
SCHEMBL922873 0.80 F10 (0.50) FDFT1MAOBLOXLOXL2F10
Hydrochloric Acid SCHEMBL921825 0.78 F10 (0.49) FDFT1MAOBLOXLOXL2F10
Water SCHEMBL924179 0.78 F10 (0.49) FDFT1MAOBLOXLOXL2F10
SCHEMBL5205314 0.78 GAA (0.60) MAOBLOXLOXL2F10DPP4
SCHEMBL8971018 0.77 FDFT1 (0.55) FDFT1SUCNR1LPAR1LPAR5
SCHEMBL8306595 0.76 ALDH1A1 (0.58) FDFT1LTA4HPTGS2NR1H3AR
SCHEMBL6230311 0.76 L3MBTL1 (0.56) FDFT1MAOBMEN1KMT2AAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 FDFT1 865/4885MAOB 3730/4885LOX 1561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.