Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 7/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28750175 | 0.83 | MAOB (0.50) | ARGABRA1GABRB2ACACBMAOA | |
| SCHEMBL19771973 | 0.80 | NOS3 (0.42) | ARNOS3NOS1GABRA1GABRB2 | |
| SCHEMBL12189123 | 0.79 | TRPV4 (0.52) | TRPV4ARNOS3NOS1MAOA | |
| SCHEMBL7787351 | 0.79 | TRPV4 (0.55) | TRPV4ARNOS3NOS1MAOA | |
| SCHEMBL8251673 | 0.79 | TRPV4 (0.52) | TRPV4GABRA1GABRB2MAOAMAOB | |
| SCHEMBL5018935 | 0.77 | PNMT (0.70) | PNMTGABRA1GABRB2CYP2C19 | |
| SCHEMBL24776881 | 0.76 | TRPV4 (0.48) | TRPV4ARNOS3NOS1MAOA | |
| SCHEMBL18130645 | 0.76 | LOXL2 (0.50) | TRPV4ARNOS3NOS1MAOA | |
| SCHEMBL11153867 | 0.76 | ALDH1A1 (0.53) | ARMAOB | |
| SCHEMBL5047623 | 0.76 | TRPV4 (0.52) | TRPV4PNMTARNOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659047-A1 | HERBICIDAL BENZENE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994005153-A1 | HERBICIDAL BENZENE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-03-17 | — | — | WO | disclosed |