Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL922088 | 0.80 | KMT2A (0.42) | MAPTPOLBSIGMAR1GSK3AGSK3B | |
| SCHEMBL919179 | 0.80 | NPC1 (0.50) | CYP19A1CYP11B1CYP11B2MAPTPOLB | |
| SCHEMBL35352 | 0.72 | CYP19A1 (0.56) | CYP19A1CYP11B1CYP11B2MAPTCYP1A2 | |
| Hydrochloric Acid SCHEMBL27713045 | 0.70 | CYP19A1 (0.54) | CYP19A1CYP11B1CYP11B2MAPTCYP1A2 | |
| Bromide SCHEMBL916244 | 0.70 | CYP19A1 (0.54) | CYP19A1CYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL27828239 | 0.70 | CYP19A1 (0.54) | CYP19A1CYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL315610 | 0.67 | GSK3A (0.44) | MAPTCYP2D6SIGMAR1LMNAGSK3A | |
| Cyanate SCHEMBL27832718 | 0.67 | CYP1A2 (0.46) | CYP19A1CYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL287568 | 0.65 | CYP11B1 (0.48) | CYP19A1CYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL11430510 | 0.65 | NPC1 (0.65) | CYP19A1CYP11B1CYP11B2MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456178-B | Application of tetrahydropyrimidine [1,2-b ] indazole-4-amine derivatives as AhR inhibitor and preparation method thereof | 北京华森英诺生物科技有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-114456178-A | Application of tetrahydropyrimidine [1,2-b ] indazole-4-amine derivative as AhR inhibitor and preparation method thereof | 重庆华森制药股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| EP-1043988-A4 | C-10 CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE AND ANTITUMOUR ACTIVITIES | HAUSER INC (US) | 2001-10-31 | — | — | EP | claimed |
| EP-1043988-A1 | C-10 CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE AND ANTITUMOUR ACTIVITIES | Hauser Inc. (US) | 2000-10-18 | — | — | EP | claimed |
| WO-1999033461-A1 | C-10 CARBON-SUBSTITUTED ARTEMISININ-LIKE TRIOXANE COMPOUNDS HAVING ANTIMALARIAL, ANTIPROLIFERATIVE AND ANTITUMOUR ACTIVITIES | HAUSER, INC. (US) | 1999-07-08 | — | — | WO | claimed |
| CN-114456178-B | Application of tetrahydropyrimidine [1,2-b ] indazole-4-amine derivatives as AhR inhibitor and preparation method thereof | 北京华森英诺生物科技有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-114456178-A | Application of tetrahydropyrimidine [1,2-b ] indazole-4-amine derivative as AhR inhibitor and preparation method thereof | 重庆华森制药股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| US-9359393-B2 | Photoresponsive nucleic acid manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-06-07 | — | — | US | disclosed |
| EP-2253640-B1 | PHOTORESPONSIVE NUCLEIC ACID MANUFACTURING METHOD | JAPAN SCIENCE & TECH AGENCY (JP) | 2014-07-30 | — | — | EP | disclosed |
| US-20140107331-A1 | PHOTORESPONSIVE NUCLEIC ACID MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-04-17 | — | — | US | disclosed |
| US-8642754-B2 | Photoresponsive nucleic acid manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-02-04 | — | — | US | disclosed |
| CN-101300250-B | Heterocyclic substituted pyridine derivative and antifungal agent containing the same | EISAI R&D MAN CO LTD | 2012-09-05 | — | — | CN | disclosed |
| US-20110040083-A1 | PHOTORESPONSIVE NUCLEIC ACID MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-02-17 | — | — | US | disclosed |
| US-20110009454-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2253640-A1 | PHOTORESPONSIVE NUCLEIC ACID MANUFACTURING METHOD | Japan Science and Technology Agency (JP) | 2010-11-24 | — | — | EP | disclosed |
| EP-2248423-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | Sumitomo Chemical Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| CN-101668767-A | Pyridine derivatives substituted with heterocyclic ring and phosphonoamino group and antifungal agent containing the same | EISAI R&D MAN CO LTD | 2010-03-10 | — | — | CN | disclosed |
| US-20100041694-A1 | AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
| CN-101300250-A | Heterocyclic substituted pyridine derivative and antifungal agent containing the same | EISAI R&D MAN CO LTD (JP) | 2008-11-05 | — | — | CN | disclosed |
| WO-2008126684-A2 | AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110040083-A1 | PHOTORESPONSIVE NUCLEIC ACID MANUFACTURING METHOD | POLRMT, POLL, POLM | CYP19A1 433/4885CYP11B1 1086/4885CYP11B2 1583/4885 |
| US-20100041694-A1 | AGRICULTURAL COMPOSITION FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENIC MICROBES | HDHD5, NAAA, BROX | CYP19A1 3009/4885CYP11B1 3464/4885CYP11B2 3688/4885 |
| US-20110009454-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | WIZ, TST, NAT1 | CYP19A1 4327/4885CYP11B1 1179/4885CYP11B2 1349/4885 |
| US-20140107331-A1 | PHOTORESPONSIVE NUCLEIC ACID MANUFACTURING METHOD | POLRMT, POLL, POLM | CYP19A1 433/4885CYP11B1 1086/4885CYP11B2 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.