Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.44 |
| ▸ | CHRNG | P07510 | 3/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.44 |
| ▸ | CHRND | Q07001 | 3/20 | 0.44 |
| ▸ | NMT2 | O60551 | 4/20 | 0.42 |
| ▸ | NMT1 | P30419 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129699 | 0.76 | ITGB3 (0.64) | ITGB3ITGA2BCNR2CHRNA1CHRNG | |
| SCHEMBL22129697 | 0.76 | ITGB3 (0.64) | ITGB3ITGA2BCNR2CHRNA1CHRNG | |
| SCHEMBL13271590 | 0.76 | SIRT6 (0.44) | NMT2NMT1CA1CA2HPGDS | |
| SCHEMBL20637849 | 0.76 | ITGB3 (0.54) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 | |
| SCHEMBL9203094 | 0.75 | CHRND (0.54) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 | |
| SCHEMBL9277061 | 0.75 | HTT (0.54) | ITGB3ITGA2BCNR2CA1CA2 | |
| SCHEMBL13512634 | 0.75 | SIRT6 (0.47) | NMT2NMT1GRIA1HPGDS | |
| SCHEMBL13176786 | 0.75 | SLC6A5 (0.49) | NMT2NMT1HPGDS | |
| SCHEMBL8269335 | 0.74 | HPGDS (0.56) | ITGB3ITGA2BCA1CA2LNPEP | |
| SCHEMBL9203772 | 0.73 | ITGB3 (0.54) | ITGB3ITGA2BCNR2CHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | MYRIAD PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | TPSAB1, TPSB2, TPSD1 | ITGB3 422/4885ITGA2B 1361/4885CNR2 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.