SCHEMBL920380

SCHEMBL920380

Fc1[c]ccc(OCc2ccncc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
AR P10275 1/20 0.40
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40
MEN1 O00255 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
TLR4 O00206 1/20 0.40
TLR2 O60603 1/20 0.40
MAOA P21397 1/20 0.39
EPHX2 P34913 1/20 0.38
F2 P00734 2/20 0.38
KCNH2 Q12809 1/20 0.38
GRIN2B Q13224 1/20 0.38
SLC2A1 P11166 1/20 0.37
MAOB P27338 2/20 0.36
CYP27B1 O15528 1/20 0.36
CYP24A1 Q07973 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919898 0.83 MAOB (0.53) MAOAMAOB
SCHEMBL920621 0.83 ALOX5 (0.51) SMN1; SMN2MEN1KMT2AMAOAMAOB
SCHEMBL920402 0.82 MAPK1 (0.47) MAPK1MAOAIKBKB
SCHEMBL920605 0.81 MAOB (0.51) SMN1; SMN2ARMAOAMAOB
SCHEMBL7245835 0.81 NOS3 (0.46) SMN1; SMN2ARNOS3NOS1NOS2
SCHEMBL921029 0.81 MAOB (0.49) MAOAMAOB
SCHEMBL920432 0.80 ACHE (0.43) MAOAMAOB
SCHEMBL920022 0.79 MAOB (0.53) SMN1; SMN2MAOB
SCHEMBL919526 0.77 MAOB (0.51) MAOAMAOB
SCHEMBL921277 0.76 MAOB (0.59) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 SMN1; SMN2 4796/4885AR 4285/4885NOS3 263/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 SMN1; SMN2 4604/4885AR 1048/4885NOS3 920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.