SCHEMBL920462

SCHEMBL920462

Nc1ncccc1C(=O)NCc1ccc(Oc2cccc(I)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.53
HPGD P15428 3/20 0.47
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
CYP3A4 P08684 1/20 0.44
HTT P42858 1/20 0.44
MMP13 P45452 1/20 0.44
MAPK14 Q16539 1/20 0.44
NSD2 O96028 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921817 0.93 HPGD (0.53) MAPK8HPGDKMT2AALDH1A1MEN1
SCHEMBL920221 0.90 MAPK8 (0.55) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL920985 0.89 MAPK8 (0.53) MAPK8HPGDKMT2AALDH1A1MEN1
SCHEMBL920461 0.88 MAPK8 (0.67) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL920714 0.87 MAPK8 (0.53) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL921448 0.87 MAPK8 (0.53) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL920269 0.87 MAPK8 (0.53) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL920561 0.87 MAPK8 (0.53) MAPK8HPGDLMNASMN1; SMN2ALDH1A1
SCHEMBL921271 0.87 HPGD (0.57) MAPK8HPGDLMNASMN1; SMN2KMT2A
SCHEMBL919798 0.86 MAPK8 (0.55) MAPK8HPGDLMNASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK8 2313/4885HPGD 1273/4885LMNA 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.