Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204729 | 0.85 | KDM2B (0.43) | KDM2BHTR1ASLC6A4MAOAMAOB | |
| SCHEMBL9738921 | 0.73 | HTR1A (0.48) | HTR1ASLC6A4KMT2AABCB1 | |
| SCHEMBL9739469 | 0.71 | ABCB1 (0.55) | HTR1ASLC6A4ABCB1 | |
| SCHEMBL9211782 | 0.71 | DHCR7 (0.51) | KDM2BABCB1 | |
| Bromide SCHEMBL9206535 | 0.70 | KDM2B (0.39) | KDM2BHTR1ASLC6A4ABCB1 | |
| SCHEMBL9212460 | 0.69 | BCHE (0.49) | KMT2AMAOAMAOBSLC2A1 | |
| SCHEMBL9739714 | 0.69 | MEN1 (0.38) | HTR1ASLC6A4KMT2A | |
| SCHEMBL9214315 | 0.68 | ABCB1 (0.56) | HTR1ASLC6A4ABCB1 | |
| SCHEMBL9209353 | 0.67 | KDM2B (0.44) | KDM2BKMT2AMAOAMAOB | |
| SCHEMBL9211699 | 0.67 | KDM2B (0.44) | KDM2BKMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |