Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738921 | 0.88 | HTR1A (0.48) | HTR1ASLC6A4KDM4EALDH1A1STAT3 | |
| SCHEMBL9204735 | 0.85 | KDM2B (0.41) | KDM2BHTR1ASLC6A4MAOAMAOB | |
| SCHEMBL9739714 | 0.83 | MEN1 (0.38) | HTR1ASLC6A4 | |
| SCHEMBL9740195 | 0.80 | DRD2 (0.43) | HTR1ASLC6A4CA12CA1CA2 | |
| SCHEMBL9739469 | 0.79 | ABCB1 (0.55) | HTR1ASLC6A4ABCB1 | |
| SCHEMBL9211782 | 0.75 | DHCR7 (0.51) | KDM2BKDM4EABCB1 | |
| SCHEMBL9207731 | 0.75 | SIGMAR1 (0.43) | HTR1AACHE | |
| SCHEMBL9216372 | 0.74 | MEN1 (0.42) | HTR1ASLC6A4KDM4EALDH1A1ACHE | |
| Bromide SCHEMBL9206535 | 0.72 | KDM2B (0.39) | KDM2BHTR1ASLC6A4BCHEACHE | |
| SCHEMBL10762123 | 0.72 | HTR1A (0.56) | HTR1ASLC6A4KDM4EMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292840-B1 | Cyclic amine derivatives, medicaments containing these compounds and procedure for their preparation | THOMAE GMBH DR K (DE) | 1995-08-09 | — | — | EP | disclosed |