Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204729 | 0.83 | KDM2B (0.43) | HTR1ASLC6A4 | |
| SCHEMBL9738921 | 0.79 | HTR1A (0.48) | MEN1KMT2AHTR1ASLC6A4SIGMAR1 | |
| SCHEMBL9216372 | 0.78 | MEN1 (0.42) | MEN1KMT2AHTR1ASLC6A4DRD1 | |
| SCHEMBL9740252 | 0.78 | KMT2A (0.38) | MEN1KMT2APKMDRD4RAB9A | |
| SCHEMBL9739252 | 0.73 | KMT2A (0.42) | MEN1KMT2ARAB9A | |
| SCHEMBL9215338 | 0.72 | MEN1 (0.41) | MEN1KMT2AHTR1ADRD2DRD1 | |
| SCHEMBL9739469 | 0.72 | ABCB1 (0.55) | HTR1ASLC6A4SIGMAR1 | |
| SCHEMBL9207731 | 0.72 | SIGMAR1 (0.43) | HTR1ADRD4SIGMAR1 | |
| SCHEMBL19859669 | 0.72 | CYP2D6 (0.53) | KMT2APKMDRD2DRD1DRD4 | |
| SCHEMBL19859670 | 0.72 | CYP2D6 (0.53) | KMT2APKMDRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |