Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227562 | 0.87 | IDO1 (0.49) | NR4A2NPC1RAB9AMAOBMAOA | |
| SCHEMBL27650144 | 0.83 | NR4A2 (0.41) | NR4A2NPC1RAB9AMAOBMAPT | |
| SCHEMBL22534449 | 0.83 | NR4A2 (0.53) | NR4A2IDO1MAPTMEN1KMT2A | |
| SCHEMBL6999493 | 0.81 | SMN1; SMN2 (0.53) | NR4A2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL920476 | 0.81 | NR4A2 (0.57) | NR4A2NPC1RAB9AMAOBMAOA | |
| SCHEMBL27630109 | 0.80 | RAB9A (0.46) | NR4A2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL919794 | 0.80 | MAOB (0.49) | MAOBKMT2A | |
| SCHEMBL920290 | 0.80 | MAOB (0.51) | NPC1RAB9AMAOBIDO1HTT | |
| SCHEMBL9812484 | 0.80 | NR4A2 (0.69) | NR4A2NPC1RAB9AMAOBMAOA | |
| SCHEMBL6639679 | 0.79 | CHRM2 (0.46) | TP53MEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134754-A1 | BENZOIMIDAZOLE GLYCINAMIDES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | WO | claimed |
| US-20090270398-A1 | Compounds, Compositions and Methods Comprising Pyridazine Derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2009-10-29 | — | — | US | claimed |
| WO-2009131947-A2 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING PYRIDAZINE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | claimed |
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |
| US-11618744-B2 | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2023-04-04 | — | — | US | disclosed |
| US-20210078978-A1 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-03-18 | — | — | US | disclosed |
| US-10851083-B2 | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-01 | — | — | US | disclosed |
| EP-3277674-B1 | TRIAZOL DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2019-09-11 | — | — | EP | disclosed |
| CN-105622580-B | Benzimidazole as prolyl hydroxylase inhibitors | 詹森药业有限公司 | 2019-06-21 | — | — | CN | disclosed |
| US-20180339976-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-11-29 | — | — | US | disclosed |
| US-20180215732-A9 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-08-02 | — | — | US | disclosed |
| US-20180022733-A1 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-01-25 | — | — | US | disclosed |
| EP-0945437-B1 | Pyrazolyl acrylic acid- and pyrazolyl oximino-acetic acid derivatives, their preparation and their use as fungicides | SDS BIOTECH CORP (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-20050014649-A1 | Novel substituted pyrazole derivative, process for producing the same, and herbicidal composition containing the same | SDS BIOTECH K.K. (JP) | 2005-01-20 | — | — | US | disclosed |
| US-6809065-B2 | ON ALGAE OR WEEDS; CROP SELECTIVITY | SDS BIOTECH K.K. (JP) | 2004-10-26 | — | — | US | disclosed |
| EP-1464642-A1 | NOVEL SUBSTITUTED PYRAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND HERBICIDAL COMPOSITION CONTAINING THE SAME | SDS Biotech K.K. (JP) | 2004-10-06 | — | — | EP | disclosed |
| EP-1407667-A1 | HERBICIDE CONTAINING SUBSTITUTED PYRAZOLE DERIVATIVE AS ACTIVE INGREDIENT | SDS Biotech K.K. (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-20040033898-A1 | Herbicide containing substituted pyrazole derivative as active ingredient | SDS BIOTECH K.K. (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-0945437-A1 | Pyrazolyl acrylic acid- and pyrazolyl oximino-acetic acid derivatives, their preparation and their use as fungicides | SDS Biotech K.K. (JP) | 1999-09-29 | — | — | EP | disclosed |
| CN-1122800-A | Pyrimidinyl acrylic acid derivatives | SANDOZ LTD (CH) | 1996-05-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11618744-B2 | Benzoimidazoles as prolyl hydroxylase inhibitors | P4HA1, PAH, EGLN3 | NR4A2 2078/4885NPC1 1042/4885RAB9A 3990/4885 |
| US-20180339976-A1 | NOVEL TRIAZOLE DERIVATIVES | ERG28, CYP51A1, SBK3 | NR4A2 1505/4885NPC1 3654/4885RAB9A 3186/4885 |
| US-20090270398-A1 | Compounds, Compositions and Methods Comprising Pyridazine Derivatives | CFTR, PKD1, PKD2 | NR4A2 2709/4885NPC1 518/4885RAB9A 2706/4885 |
| US-20180022733-A1 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | P4HA1, PAH, EGLN3 | NR4A2 2078/4885NPC1 1042/4885RAB9A 3990/4885 |
| US-20050014649-A1 | Novel substituted pyrazole derivative, process for producing the same, and herbicidal composition containing the same | HPD, HDHD5, CYP2E1 | NR4A2 2029/4885NPC1 4397/4885RAB9A 2379/4885 |
| US-10851083-B2 | Benzoimidazoles as prolyl hydroxylase inhibitors | P4HA1, PAH, EGLN3 | NR4A2 2078/4885NPC1 1042/4885RAB9A 3990/4885 |
| US-20180215732-A9 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | P4HA1, PAH, EGLN3 | NR4A2 2078/4885NPC1 1042/4885RAB9A 3990/4885 |
| US-20210078978-A1 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | P4HA1, PAH, EGLN3 | NR4A2 2078/4885NPC1 1042/4885RAB9A 3990/4885 |
| US-20040033898-A1 | Herbicide containing substituted pyrazole derivative as active ingredient | DDT, SULT2A1, CYP2E1 | NR4A2 2644/4885NPC1 4723/4885RAB9A 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.