Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206968 | 0.86 | HPGD (0.40) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9198152 | 0.82 | HPGD (0.37) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9205868 | 0.79 | KMT2A (0.46) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9592251 | 0.74 | CYP1A2 (0.43) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9199703 | 0.73 | POLB (0.37) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL9526741 | 0.72 | LMNA (0.43) | HPGDKMT2AMEN1HTTL3MBTL1 | |
| SCHEMBL13214815 | 0.69 | LIPE (0.51) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3417324 | 0.69 | GAA (0.37) | KMT2AMEN1HTTTSHRL3MBTL1 | |
| SCHEMBL9591673 | 0.69 | CYP1A2 (0.41) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL9526216 | 0.68 | ALDH1A1 (0.37) | NPC1RAB9AHTTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418667-B1 | Carboxylic acid amides | BASF AG (DE) | 1995-08-16 | — | — | EP | disclosed |
| EP-0418667-A2 | Carboxylic acid amides | BASF Aktiengesellschaft (DE) | 1991-03-27 | — | — | EP | disclosed |