Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201897 | 0.81 | PRKAB2 (0.32) | SMN1; SMN2GABRA5NPY1R | |
| SCHEMBL9198077 | 0.81 | NPY1R (0.30) | ALDH1A1SMN1; SMN2KDM4EGABRA5NPY1R | |
| SCHEMBL9527271 | 0.81 | ALDH1A1 (0.33) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL9526741 | 0.80 | LMNA (0.43) | ALDH1A1SMN1; SMN2KDM4EHTTL3MBTL1 | |
| SCHEMBL9203070 | 0.79 | GABRA5 (0.38) | ALDH1A1GABRA5RIPK1L3MBTL1 | |
| SCHEMBL9240927 | 0.78 | GAA (0.38) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL9201823 | 0.76 | ALDH1A1 (0.37) | ALDH1A1RAB9ASMN1; SMN2NPC1GABRA5 | |
| SCHEMBL9199703 | 0.76 | POLB (0.37) | RAB9ANPC1POLBHTTL3MBTL1 | |
| SCHEMBL8986729 | 0.74 | SMN1; SMN2 (0.40) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL9446181 | 0.74 | HTT (0.44) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575341-A1 | ISOXAZOL- AND ISOTHIAZOL-5-CARBOXYLIC ACID AMIDES | BASF Aktiengesellschaft (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0337263-B1 | ISOXAZOL(ISOTHIAZOLS)-5-CARBOXAMIDES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| WO-1992016514-A1 | ISOXAZOL- AND ISOTHIAZOL-5-CARBOXYLIC ACID AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-01 | — | — | WO | disclosed |
| EP-0337263-A2 | Isoxazol(isothiazols)-5-carboxamides | BASF Aktiengesellschaft (DE) | 1989-10-18 | — | — | EP | disclosed |