Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417324 | 0.77 | GAA (0.37) | GAAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL9526741 | 0.77 | LMNA (0.43) | GAAMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL9527355 | 0.76 | POLB (0.34) | POLBMEN1KMT2ANPC1L3MBTL1 | |
| SCHEMBL9526216 | 0.76 | ALDH1A1 (0.37) | POLBHTTNPC1L3MBTL1RAB9A | |
| SCHEMBL11242567 | 0.74 | L3MBTL1 (0.34) | POLBMEN1KMT2AHTTNPC1 | |
| SCHEMBL9205871 | 0.73 | HPGD (0.40) | POLBMEN1KMT2AHTTNPC1 | |
| SCHEMBL9199700 | 0.73 | POLB (0.45) | POLBGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL7030589 | 0.71 | ALDH1A1 (0.33) | GAAL3MBTL1 | |
| SCHEMBL3535408 | 0.70 | POLB (0.39) | POLBGAAMEN1KMT2AHTT | |
| SCHEMBL3625472 | 0.69 | RAB9A (0.50) | POLBGAAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418667-B1 | Carboxylic acid amides | BASF AG (DE) | 1995-08-16 | — | — | EP | disclosed |
| EP-0337263-B1 | ISOXAZOL(ISOTHIAZOLS)-5-CARBOXAMIDES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0337263-A2 | Isoxazol(isothiazols)-5-carboxamides | BASF Aktiengesellschaft (DE) | 1989-10-18 | — | — | EP | disclosed |