Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206341 | 0.77 | KMT2A (0.48) | L3MBTL1GLATDP1MAPTNPSR1 | |
| SCHEMBL7861235 | 0.73 | ALDH1A1 (0.48) | L3MBTL1TDP1MAPTMMP8MRGPRX4 | |
| SCHEMBL7860078 | 0.72 | ALDH1A1 (0.47) | L3MBTL1GLAMAPTMMP8KMT2A | |
| SCHEMBL16672964 | 0.68 | GLA (0.49) | L3MBTL1GLATDP1MAPTHCRTR1 | |
| SCHEMBL16672862 | 0.67 | L3MBTL1 (0.49) | L3MBTL1GLATDP1MAPTNPSR1 | |
| SCHEMBL9199837 | 0.67 | ALDH1A1 (0.47) | L3MBTL1TDP1MAPTMMP8POLB | |
| SCHEMBL21939443 | 0.66 | L3MBTL1 (0.59) | L3MBTL1GLATDP1MAPTNPSR1 | |
| SCHEMBL7183691 | 0.66 | RXFP1 (0.42) | L3MBTL1GLARXFP1MAPTHCRTR1 | |
| SCHEMBL6584031 | 0.65 | LMNA (0.44) | L3MBTL1MAPTNPSR1MMP8FBP1 | |
| SCHEMBL4111678 | 0.65 | FBP1 (0.58) | TDP1MMP8FBP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423802-B1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMA (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5134154-A | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0423802-A1 | Phenoxy-heterocyclic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-24 | — | — | EP | disclosed |