SCHEMBL919451

SCHEMBL919451

Fc1[c]cccc1Oc1cnccn1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
GAA P10253 1/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 2/20 0.33
PTGS2 P35354 2/20 0.33
LTA4H P09960 1/20 0.33
GRM4 Q14833 1/20 0.33
HPGD P15428 1/20 0.33
FEN1 P39748 2/20 0.32
ALOX5AP P20292 1/20 0.32
PLAU P00749 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11829984 0.81 KMT2A (0.49) KMT2AMEN1GAAMAPTKDM4E
SCHEMBL920694 0.81 KDM4E (0.49) KMT2AMEN1KDM4EPTGS2LTA4H
SCHEMBL919956 0.76 LMNA (0.47) GAASMN1; SMN2ALDH1A1LTA4HHPGD
SCHEMBL5046995 0.76 RXRA (0.35) KMT2AMEN1GAAKDM4EALDH1A1
SCHEMBL921197 0.73 CA12 (0.36) MAPTALDH1A1PTGS2
SCHEMBL1977896 0.72 KMT2A (0.42) KMT2AMEN1GAAMAPTKDM4E
SCHEMBL921640 0.72 KMT2A (0.59) KMT2AMEN1MAPTSMN1; SMN2HPGD
SCHEMBL31132631 0.71 HSPB1 (0.50) KMT2AMEN1GAAMAPTKDM4E
SCHEMBL2464288 0.70 KMT2A (0.50) KMT2AMEN1GAAMAPTKDM4E
SCHEMBL5317072 0.70 KMT2A (0.50) KMT2AMEN1GAAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 KMT2A 2469/4885MEN1 4723/4885GAA 3332/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 KMT2A 1924/4885MEN1 1798/4885GAA 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.