SCHEMBL920696

SCHEMBL920696

Nc1ncccc1C(=O)NCc1cccc(Oc2ccc3c(c2)CCC3)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.53
HPGD P15428 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
ALDH1A1 P00352 3/20 0.51
HTT P42858 2/20 0.51
LMNA P02545 2/20 0.51
USP2 O75604 2/20 0.51
TSHR P16473 1/20 0.51
MAPK1 P28482 1/20 0.51
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
KDM4E B2RXH2 2/20 0.50
KMT2A Q03164 2/20 0.48
MAPK8 P45983 1/20 0.47
GAA P10253 1/20 0.46
ROCK1 Q13464 1/20 0.44
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921729 0.98 MAPK14 (0.53) MAPK14HPGDSMN1; SMN2ALDH1A1HTT
SCHEMBL920330 0.92 MAPK14 (0.55) MAPK14HPGDSMN1; SMN2ALDH1A1HTT
SCHEMBL921470 0.91 MAPK14 (0.53) MAPK14HPGDSMN1; SMN2ALDH1A1HTT
SCHEMBL1680406 0.85 MAPK8 (0.63) MAPK14HPGDALDH1A1USP2RAB9A
SCHEMBL920985 0.84 MAPK8 (0.53) MAPK14HPGDALDH1A1USP2KDM4E
SCHEMBL921549 0.84 MAPK8 (0.53) MAPK14HPGDALDH1A1LMNAUSP2
SCHEMBL920077 0.84 HPGD (0.62) HPGDSMN1; SMN2ALDH1A1LMNAUSP2
SCHEMBL921179 0.84 MAPK8 (0.53) HPGDALDH1A1LMNAUSP2KDM4E
SCHEMBL921092 0.84 MMP13 (0.58) MAPK14HPGDALDH1A1USP2KDM4E
SCHEMBL920049 0.84 MAPK8 (0.53) MAPK14HPGDALDH1A1HTTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK14 905/4885HPGD 1273/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.