SCHEMBL921470

SCHEMBL921470

Nc1ncccc1C(=O)NCc1ccc(Oc2ccc3c(c2)CCCC3)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.53
MAPK8 P45983 1/20 0.49
SMN1; SMN2 Q16637 5/20 0.48
HPGD P15428 4/20 0.48
LMNA P02545 2/20 0.48
ALDH1A1 P00352 2/20 0.48
USP2 O75604 1/20 0.48
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALOX12 P18054 1/20 0.46
TP53 P04637 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920330 0.99 MAPK14 (0.55) MAPK14MAPK8SMN1; SMN2HPGDLMNA
SCHEMBL921729 0.93 MAPK14 (0.53) MAPK14MAPK8SMN1; SMN2HPGDLMNA
SCHEMBL920696 0.91 MAPK14 (0.53) MAPK14MAPK8SMN1; SMN2HPGDLMNA
SCHEMBL920461 0.84 MAPK8 (0.67) MAPK14MAPK8SMN1; SMN2HPGDLMNA
SCHEMBL921604 0.84 MAPK8 (0.55) MAPK8SMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL921056 0.83 LMNA (0.57) MAPK8SMN1; SMN2HPGDLMNAMAPT
SCHEMBL920002 0.83 MAPK8 (0.51) MAPK8SMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL921037 0.82 HPGD (0.66) MAPK8SMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL920473 0.82 HPGD (0.57) MAPK8SMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL920265 0.82 MAPK8 (0.55) MAPK14MAPK8SMN1; SMN2HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK14 905/4885MAPK8 2313/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.