SCHEMBL920330

SCHEMBL920330

Nc1ncccc1C(=O)NCc1ccc(Oc2ccc3c(c2)CCC3)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.55
SMN1; SMN2 Q16637 7/20 0.50
HPGD P15428 4/20 0.50
LMNA P02545 3/20 0.50
ALDH1A1 P00352 3/20 0.50
HTT P42858 3/20 0.50
USP2 O75604 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
NPC1 O15118 5/20 0.49
RAB9A P51151 5/20 0.49
KDM4E B2RXH2 1/20 0.49
MAPK8 P45983 1/20 0.48
ALOX12 P18054 1/20 0.47
MAPT P10636 2/20 0.45
TP53 P04637 1/20 0.45
RECQL P46063 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921470 0.99 MAPK14 (0.53) MAPK14SMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL920696 0.92 MAPK14 (0.53) MAPK14SMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL921729 0.92 MAPK14 (0.53) MAPK14SMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL920461 0.84 MAPK8 (0.67) MAPK14SMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL921604 0.83 MAPK8 (0.55) SMN1; SMN2HPGDLMNAALDH1A1MAPK8
SCHEMBL920002 0.82 MAPK8 (0.51) SMN1; SMN2HPGDLMNAALDH1A1HTT
SCHEMBL921056 0.82 LMNA (0.57) SMN1; SMN2HPGDLMNAMAPK8MAPT
SCHEMBL920265 0.82 MAPK8 (0.55) MAPK14SMN1; SMN2HPGDLMNAALDH1A1
SCHEMBL921037 0.82 HPGD (0.66) SMN1; SMN2HPGDLMNAALDH1A1RAB9A
SCHEMBL920343 0.82 KMT2A (0.61) MAPK14SMN1; SMN2HPGDLMNAMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK14 905/4885SMN1; SMN2 4796/4885HPGD 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.