SCHEMBL922079

SCHEMBL922079

COCc1ccc(C(=O)NCc2ccc(Oc3ccc(C)cc3)cc2)c(N)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 2/20 0.50
MMP13 P45452 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
MMP2 P08253 1/20 0.49
CYP3A4 P08684 1/20 0.49
STAT3 P40763 1/20 0.49
HTT P42858 1/20 0.49
HPGD P15428 3/20 0.47
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPT P10636 2/20 0.45
RXFP1 Q9HBX9 2/20 0.45
CHRNA7 P36544 1/20 0.43
TP53 P04637 2/20 0.41
EGLN1 Q9GZT9 1/20 0.41
CHRM4 P08173 1/20 0.41
FLT1 P17948 1/20 0.41
LRRK2 Q5S007 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922841 0.92 EGLN1 (0.49) SMN1; SMN2HPGDALDH1A1KDM4ERXFP1
SCHEMBL919997 0.91 MAPK14 (0.50) MAPK14MMP13SMN1; SMN2CYP3A4HTT
SCHEMBL920018 0.91 TP53 (0.41) MAPK14MMP13SMN1; SMN2MMP2CYP3A4
SCHEMBL920779 0.90 LIPG (0.51) MAPK14SMN1; SMN2CYP3A4HTTMAPT
SCHEMBL920636 0.90 CYP3A4 (0.48) MAPK14SMN1; SMN2CYP3A4HTTHPGD
SCHEMBL920880 0.90 EGLN1 (0.41) MAPK14MMP13SMN1; SMN2MMP2CYP3A4
SCHEMBL921652 0.90 AKR1B1 (0.41) MAPK14MMP13SMN1; SMN2MMP2CYP3A4
SCHEMBL921782 0.90 MAPK14 (0.45) MAPK14MMP13CYP3A4HPGDALDH1A1
SCHEMBL920812 0.90 MMP13 (0.56) MAPK14MMP13SMN1; SMN2MMP2CYP3A4
SCHEMBL922173 0.89 POLB (0.48) SMN1; SMN2CYP3A4HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK14 905/4885MMP13 4062/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.