SCHEMBL920880

SCHEMBL920880

COCc1ccc(C(=O)NCc2ccc(Oc3ccc(I)cc3)cc2)c(N)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.41
KMT2A Q03164 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
MAPK14 Q16539 2/20 0.39
HPGD P15428 4/20 0.39
ALDH1A1 P00352 1/20 0.39
MMP13 P45452 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MMP2 P08253 1/20 0.38
CYP3A4 P08684 1/20 0.38
STAT3 P40763 1/20 0.38
HTT P42858 1/20 0.38
CHRM4 P08173 2/20 0.38
FLT1 P17948 1/20 0.38
LRRK2 Q5S007 1/20 0.38
GALR3 O60755 1/20 0.38
NR2F2 P24468 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922841 0.91 EGLN1 (0.49) EGLN1KMT2AHPGDALDH1A1SMN1; SMN2
SCHEMBL920018 0.90 TP53 (0.41) EGLN1KMT2ALIPGMAPK14HPGD
SCHEMBL919997 0.90 MAPK14 (0.50) EGLN1LIPGMAPK14HPGDALDH1A1
SCHEMBL922079 0.90 MAPK14 (0.50) EGLN1KMT2AMAPK14HPGDALDH1A1
SCHEMBL922486 0.90 HPGD (0.47) KMT2AMAPK14HPGDALDH1A1MMP13
SCHEMBL919232 0.90 KDM4E (0.40) EGLN1KMT2AMAPK14HPGDALDH1A1
SCHEMBL920779 0.89 LIPG (0.51) LIPGMAPK14SMN1; SMN2CYP3A4HTT
SCHEMBL921652 0.89 AKR1B1 (0.41) EGLN1KMT2ALIPGMAPK14HPGD
SCHEMBL920636 0.89 CYP3A4 (0.48) EGLN1KMT2AMAPK14HPGDALDH1A1
SCHEMBL922173 0.88 POLB (0.48) EGLN1HPGDSMN1; SMN2CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 EGLN1 430/4885KMT2A 2469/4885LIPG 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.