SCHEMBL922841

SCHEMBL922841

COCc1ccc(C(=O)NCc2ccc(Oc3ccc(OC)cc3)cc2)c(N)n1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.49
KMT2A Q03164 1/20 0.47
HPGD P15428 6/20 0.47
ALDH1A1 P00352 1/20 0.47
CHRM4 P08173 4/20 0.46
FLT1 P17948 1/20 0.46
LRRK2 Q5S007 1/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALOX15 P16050 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922079 0.92 MAPK14 (0.50) EGLN1KMT2AHPGDALDH1A1CHRM4
SCHEMBL919997 0.92 MAPK14 (0.50) EGLN1HPGDALDH1A1LMNASMN1; SMN2
SCHEMBL920018 0.92 TP53 (0.41) EGLN1KMT2AHPGDALDH1A1CHRM4
SCHEMBL922036 0.92 KDM4E (0.48) EGLN1KMT2AHPGDALDH1A1RXFP1
SCHEMBL920779 0.91 LIPG (0.51) LMNASMN1; SMN2L3MBTL1
SCHEMBL920880 0.91 EGLN1 (0.41) EGLN1KMT2AHPGDALDH1A1CHRM4
SCHEMBL920636 0.91 CYP3A4 (0.48) EGLN1KMT2AHPGDALDH1A1CHRM4
SCHEMBL921652 0.91 AKR1B1 (0.41) EGLN1KMT2AHPGDALDH1A1CHRM4
SCHEMBL922173 0.90 POLB (0.48) EGLN1HPGDLMNASMN1; SMN2RXFP1
SCHEMBL920715 0.90 EGLN1 (0.40) EGLN1KMT2AHPGDALDH1A1CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 EGLN1 430/4885KMT2A 2469/4885HPGD 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.