Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209686 | 0.78 | FABP7 (0.36) | NOTUMCES2CES1AADAT | |
| SCHEMBL7595980 | 0.78 | MTNR1A (0.40) | AADATMAPT | |
| SCHEMBL12060765 | 0.74 | NOTUM (0.37) | NOTUMCES2CES1AADATPOLB | |
| SCHEMBL30306223 | 0.73 | DRD2 (0.45) | NOTUMCES2CES1AADATNOS3 | |
| SCHEMBL6404425 | 0.73 | RYR2 (0.41) | NOTUMGAAMAPTMCL1KMT2A | |
| SCHEMBL4014532 | 0.73 | DRD2 (0.45) | NOTUMCES2CES1AADATNOS3 | |
| SCHEMBL9220554 | 0.69 | MALT1 (0.45) | NOTUMTSHRSMN1; SMN2 | |
| SCHEMBL7598057 | 0.68 | ACHE (0.40) | POLBMAPTKMT2ALMNAHPGD | |
| SCHEMBL289302 | 0.67 | AKR1C3 (0.50) | NOTUMCES2CES1GAAMAPT | |
| SCHEMBL29443025 | 0.67 | AKR1C3 (0.50) | NOTUMCES2CES1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389425-B1 | Benzotiopyranyl amines | CIBA GEIGY AG (CH) | 1995-04-26 | — | — | EP | disclosed |
| US-5071858-A | Antipsychotic benzothiopyranylamines | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0389425-A1 | Benzotiopyranyl amines | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |