Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595980 | 0.82 | MTNR1A (0.40) | ACHECYP1A2MAPTMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7600425 | 0.75 | ADRA1A (0.42) | ACHEKDM4ELMNA | |
| SCHEMBL7600585 | 0.75 | MTNR1A (0.47) | CYP1A2MAPTNQO2MTNR1AMTNR1B | |
| SCHEMBL7590712 | 0.70 | SMN1; SMN2 (0.42) | ACHEKDM4EMTNR1AMTNR1BCA1 | |
| Hydrochloric Acid SCHEMBL7597212 | 0.69 | DRD2 (0.45) | ACHEPOLB | |
| SCHEMBL9209684 | 0.68 | NOTUM (0.38) | MAPTLMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL9213535 | 0.68 | RYR2 (0.49) | SMN1; SMN2 | |
| SCHEMBL9763023 | 0.68 | CYP1A2 (0.46) | ACHECYP1A2MAPTMTNR1AMTNR1B | |
| SCHEMBL7220847 | 0.67 | ALDH1A1 (0.48) | ACHECYP1A2MAPTKDM4ECA1 | |
| SCHEMBL7363210 | 0.65 | CYP1A2 (0.59) | ACHECYP1A2MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781280-B1 | DERIVATIVES OF BENZOPYRAN AND OF BENZOTHIOPYRAN, THEIR PREPARATION AND THEIR USE AS AGONISTS OF DOPAMINERGIC RECEPTORS | ZAMBON SPA (IT) | 2002-11-06 | — | — | EP | disclosed |