Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.40 |
| ▸ | BCHE | P06276 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209499 | 0.86 | ALDH1A1 (0.43) | ALDH1A1HSD17B10 | |
| SCHEMBL9210057 | 0.82 | CA12 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL9209783 | 0.81 | GRM2 (0.44) | — | |
| SCHEMBL9208921 | 0.81 | HTR1A (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL9211643 | 0.80 | MIF (0.34) | ALDH1A1 | |
| SCHEMBL9204457 | 0.80 | MIF (0.34) | ALDH1A1 | |
| SCHEMBL9211673 | 0.79 | SLC6A2 (0.44) | ALDH1A1 | |
| SCHEMBL9205120 | 0.78 | BACE1 (0.40) | — | |
| SCHEMBL9214055 | 0.76 | MIF (0.34) | — | |
| SCHEMBL9204689 | 0.76 | ALOX5 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425209-B1 | Naphthyloxazolidone derivatives | TANABE SEIYAKU CO (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-5332754-A | Antidepressant | TANABE SEIYAKU CO., LTD. (JP) | 1994-07-26 | — | — | US | disclosed |
| US-5182296-A | Antidepressants | TANABE SEIYAKY CO., LTD. (JP) | 1993-01-26 | — | — | US | disclosed |