Water

Water

SCHEMBL921065

O.O.O.[Pt]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL29450508 1.00
Water SCHEMBL8819989 1.00
Water SCHEMBL29450509 1.00
Water SCHEMBL24591 1.00
Water SCHEMBL9088259 1.00
Water SCHEMBL20838529 1.00
Water SCHEMBL185265 1.00
Water SCHEMBL2418009 1.00
Water SCHEMBL733305 1.00
Water SCHEMBL6510201 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116273146-A Catalyst for catalyzing hydrolysis reaction of carbon disulfide and/or carbon oxysulfide in coal gas at normal temperature and application method thereof 湘潭大学 2023-06-23 CN claimed
CN-215896039-U Flame-retardant high-temperature-resistant fireproof cable 无锡市登峰电缆有限公司 2022-02-22 CN claimed
CN-102020679-A Method for preparing lobaplatin trihydrate by usingoxalate GUIZHOU YIBAI PHARMACEUTICAL 2011-04-20 CN claimed
CN-116273146-A Catalyst for catalyzing hydrolysis reaction of carbon disulfide and/or carbon oxysulfide in coal gas at normal temperature and application method thereof 湘潭大学 2023-06-23 CN disclosed
CN-108440515-B Substituted benzofuranyl and benzoxazolyl compounds and uses thereof 卡尔约药物治疗公司 2022-05-03 CN disclosed
CN-215896039-U Flame-retardant high-temperature-resistant fireproof cable 无锡市登峰电缆有限公司 2022-02-22 CN disclosed
CN-111307797-A Combined determination method for tungsten and silicon content in ferrotungsten 西宁特殊钢股份有限公司 2020-06-19 CN disclosed
CN-105198932-B Lobaplatin dihydrate, preparation method and medicinal application 贵州益佰制药股份有限公司 2018-09-21 CN disclosed
CN-105440082-B A kind of lobaplatin crystal, preparation method and medicinal application 贵州益佰制药股份有限公司 2018-08-14 CN disclosed
CN-105218587-B A kind of lobaplatin crystal, preparation method and medicinal application 贵州益佰制药股份有限公司 2018-08-14 CN disclosed
CN-105440083-B A kind of lobaplatin crystal, preparation method and medicinal application 贵州益佰制药股份有限公司 2018-08-14 CN disclosed
CN-102093226-A Preparation method of diaminomethyl cyclobutane oxalate GUIZHOU YIBAI PHARMACEUTICAL 2011-06-15 CN disclosed
CN-102020679-A Method for preparing lobaplatin trihydrate by usingoxalate GUIZHOU YIBAI PHARMACEUTICAL 2011-04-20 CN disclosed
US-7867353-B2 Thermally and electrically conductive interface AMERICAN STANDARD CIRCUITS (US) 2011-01-11 US disclosed
CN-101787052-A Method for preparing hydroxy carboxylic acid platinum complexes HANGZHOU MINSHENG PHARM GROUP 2010-07-28 CN disclosed
US-7527873-B2 To bond a high or low frequency circuit board with a heat sink; useful in printed circuit board (PCB) assemblies that operate at various frequencies; high frequency applications such as in wireless communication systems and/or Radio frequency systems; dimethylpolysiloxane, metal, catalyst, fire retardant AMERICAN STANDARD CIRCUITS (US) 2009-05-05 US disclosed
US-20080251199-A1 Thermally and Electrically Conductive Interface AMERICAN STANDARD CIRCUITS (US) 2008-10-16 US disclosed
US-20070184289-A1 Thermally and electrically conductive interface AMERICAN STANDARD CIRCUITS (US) 2007-08-09 US disclosed
US-4205392-A Gas discharge display device OWENS-ILLINOIS, INC. (US) 1980-05-27 US disclosed
US-3996489-A Gas discharge device including transition metal element on internal dielectric layer OWENS-ILLINOIS, INC. (US) 1976-12-07 US disclosed