SCHEMBL921131

SCHEMBL921131

CP(=O)(CC=O)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
SRC P12931 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
PKM P14618 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HTT P42858 1/20 0.41
HPGD P15428 2/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 2/20 0.40
ANPEP P15144 1/20 0.39
LAP3 P28838 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL923636 0.83 CYP3A4 (0.53) MEN1KMT2AHPGDKDM4ELMNA
SCHEMBL3628765 0.81 AOX1 (0.49) L3MBTL1SRCTDP1PKMMEN1
SCHEMBL4452184 0.80 SRC (0.48) L3MBTL1SRCTDP1MEN1KMT2A
SCHEMBL5483772 0.78 L3MBTL1 (0.55) L3MBTL1SRCTDP1PKMMEN1
SCHEMBL5491492 0.74 L3MBTL1 (0.52) L3MBTL1SRCTDP1PKMMEN1
SCHEMBL922430 0.74 TSHR (0.52) SRCPKMKDM4E
SCHEMBL14439890 0.73 L3MBTL1 (0.46) L3MBTL1SRCTDP1PKMMEN1
SCHEMBL676524 0.72 SRC (0.58) L3MBTL1SRCTDP1PKMMEN1
SCHEMBL310184 0.72 SRC (0.58) L3MBTL1SRCTDP1PKMMEN1
SCHEMBL5490967 0.72 L3MBTL1 (0.49) L3MBTL1SRCTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2138502-B1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID MEIJI SEIKA PHARMA CO LTD (JP) 2014-02-19 EP disclosed
US-8329935-B2 Process for producing phosphorus-containing dehydroamino acid MEJI SEIKA KAISHA LTD. (JP) 2012-12-11 US disclosed
CN-101636402-B Method for producing phosphorus-containing dehydroamino acid MEIJI SEIKA KAISHA JP 2012-04-18 CN disclosed
US-20110009662-A1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID MEIJI SEIKA KAISHA LTD. (JP) 2011-01-13 US disclosed
EP-2138502-A1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID Meiji Seika Kaisha Ltd. (JP) 2009-12-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009662-A1 PROCESS FOR PRODUCING PHOSPHORUS-CONTAINING DEHYDROAMINO ACID AMPD2, AMPD1, AMPD3 L3MBTL1 929/4885SRC 3364/4885TDP1 2725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.