Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214996 | 0.95 | ITGB3 (0.33) | GAASLC6A2SLC6A4SLC6A9P2RX7 | |
| SCHEMBL9216670 | 0.90 | P2RX7 (0.33) | GAASLC6A2SLC6A4ALDH1A1P2RX7 | |
| SCHEMBL9211995 | 0.87 | GRIA2 (0.32) | GAASLC6A2SLC6A4CYP1A2ALDH1A1 | |
| SCHEMBL9217629 | 0.85 | SLC1A3 (0.36) | ALDH1A1SMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL9211998 | 0.85 | ALDH1A1 (0.38) | GAACYP2C19ALDH1A1P2RX7SMN1; SMN2 | |
| SCHEMBL9219652 | 0.85 | ALDH1A1 (0.38) | GAACYP2C19ALDH1A1P2RX7SMN1; SMN2 | |
| SCHEMBL9216847 | 0.83 | TSHR (0.38) | GAAALDH1A1MAPTKMT2A | |
| SCHEMBL9211109 | 0.82 | MEN1 (0.37) | GAAALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL9219765 | 0.82 | ALDH1A1 (0.39) | GAACYP2C19ALDH1A1TBXAS1HSD11B1 | |
| SCHEMBL9210074 | 0.82 | PKM (0.32) | ALDH1A1P2RX7HSD11B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |