Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212819 | 0.96 | NR1H4 (0.35) | NAMPTALDH1A1P2RX7MEN1KMT2A | |
| SCHEMBL9219311 | 0.93 | EPHX2 (0.38) | NAMPTALDH1A1MEN1KMT2A | |
| SCHEMBL9211998 | 0.90 | ALDH1A1 (0.38) | NAMPTALDH1A1P2RX7SMN1; SMN2MEN1 | |
| SCHEMBL9219652 | 0.90 | ALDH1A1 (0.38) | NAMPTALDH1A1P2RX7SMN1; SMN2MEN1 | |
| SCHEMBL9211543 | 0.89 | P2RX7 (0.34) | NAMPTALDH1A1P2RX7SMN1; SMN2ITGA4 | |
| SCHEMBL9217629 | 0.86 | SLC1A3 (0.36) | NAMPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9211109 | 0.83 | MEN1 (0.37) | NAMPTALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL9219765 | 0.83 | ALDH1A1 (0.39) | NAMPTALDH1A1MEN1KMT2A | |
| SCHEMBL9215115 | 0.81 | KEAP1 (0.39) | NAMPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9211996 | 0.81 | MAPK1 (0.41) | NAMPTALDH1A1KDM4EP2RX7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |