Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211995 | 0.93 | GRIA2 (0.32) | P2RX7ALDH1A1SLC6A2SLC6A4GAA | |
| SCHEMBL9217629 | 0.91 | SLC1A3 (0.36) | ALDH1A1MEN1KMT2AHCRTR2SMN1; SMN2 | |
| SCHEMBL9219652 | 0.91 | ALDH1A1 (0.38) | P2RX7ALDH1A1GAACNR2MEN1 | |
| SCHEMBL9211998 | 0.91 | ALDH1A1 (0.38) | P2RX7ALDH1A1GAACNR2MEN1 | |
| SCHEMBL9214348 | 0.90 | GAA (0.33) | P2RX7ALDH1A1SLC6A2SLC6A4GAA | |
| SCHEMBL9210074 | 0.89 | PKM (0.32) | P2RX7ALDH1A1KMT2A | |
| SCHEMBL9219765 | 0.88 | ALDH1A1 (0.39) | ALDH1A1GAAPTGS1MEN1KMT2A | |
| SCHEMBL9211109 | 0.88 | MEN1 (0.37) | ALDH1A1GAAMEN1KMT2APTGS2 | |
| SCHEMBL9214996 | 0.88 | ITGB3 (0.33) | P2RX7SLC6A2SLC6A4GAACNR2 | |
| SCHEMBL9216847 | 0.87 | TSHR (0.38) | ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |