Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17126854 | 0.90 | TSHR (0.49) | THRBTSHRACHEPOLBAPEX1 | |
| SCHEMBL92093 | 0.88 | THRB (0.43) | THRBTSHRACHE | |
| SCHEMBL14984891 | 0.88 | THRB (0.46) | THRBTSHRACHEALDH1A1L3MBTL1 | |
| SCHEMBL2403793 | 0.87 | THRB (0.53) | THRBTSHRACHEALDH1A1L3MBTL1 | |
| SCHEMBL13872030 | 0.87 | THRB (0.53) | THRBTSHRACHEALDH1A1L3MBTL1 | |
| SCHEMBL19343428 | 0.86 | ACHE (0.40) | ACHELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL25353869 | 0.84 | THRB (0.46) | THRBTSHRACHEALDH1A1LMNA | |
| SCHEMBL14368843 | 0.84 | TSHR (0.58) | THRBTSHRACHEPOLBAPEX1 | |
| SCHEMBL4087391 | 0.84 | THRB (0.55) | THRBTSHRACHEALDH1A1L3MBTL1 | |
| SCHEMBL10057616 | 0.84 | TSHR (0.53) | THRBTSHRACHEPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248651-A1 | METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-08-10 | — | — | US | disclosed |
| US-11642313-B2 | Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-05-09 | — | — | US | disclosed |
| US-9902818-B2 | Isolated and fixed micro and nano structures and methods thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-02-27 | — | — | US | disclosed |
| US-9877920-B2 | Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2018-01-30 | — | — | US | disclosed |
| US-20170259461-A1 | Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2017-09-14 | — | — | US | disclosed |
| US-9662809-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160236379-A1 | Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-9340001-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9314548-B2 | Nanostructured surfaces for biomedical/biomaterial applications and processes thereof | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20160038418-A1 | NANOPARTICLE FABRICATION METHODS, SYSTEMS, AND MATERIALS | NATIONAL SCIENCE FOUNDATION | 2016-02-11 | — | — | US | disclosed |
| US-8439666-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2013-05-14 | — | — | US | disclosed |
| US-8420124-B2 | Methods for fabricating isolated micro- and nano-structures using soft or imprint lithography | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-04-16 | — | — | US | disclosed |
| US-20120256354-A1 | METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-10-11 | — | — | US | disclosed |
| US-8268446-B2 | Photocurable perfluoropolyethers for use as novel materials in microfluidic devices | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-09-18 | — | — | US | disclosed |
| US-8263129-B2 | Methods for fabricating isolated micro-and nano-structures using soft or imprint lithography | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-09-11 | — | — | US | disclosed |
| US-20120189728-A1 | METHODS AND MATERIALS FOR FABRICATING LAMINATE NANOMOLDS AND NANOPARTICLES THEREFROM | LIQUIDIA TECHNOLOGIES, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-8158728-B2 | Methods and materials for fabricating microfluidic devices | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-04-17 | — | — | US | disclosed |
| US-8128393-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110182805-A1 | Nanoparticle fabrication methods, systems, and materials | NATIONAL SCIENCE FOUNDATION | 2011-07-28 | — | — | US | disclosed |
| US-20090304992-A1 | Micro and Nano-Structure Metrology | LABORATORY CORPORATION OF AMERICA HOLDINGS | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11642313-B2 | Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography | PFN1, FLNA, FSCN1 | THRB 4224/4885TSHR 3300/4885ACHE 3523/4885 |
| US-20230248651-A1 | METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY | PFN1, FLNA, FSCN1 | THRB 4224/4885TSHR 3300/4885ACHE 3523/4885 |
| US-20160038418-A1 | NANOPARTICLE FABRICATION METHODS, SYSTEMS, AND MATERIALS | TTN, TAGLN2, TLN1 | THRB 2627/4885TSHR 840/4885ACHE 2743/4885 |
| US-20110182805-A1 | Nanoparticle fabrication methods, systems, and materials | TTN, TAGLN2, TLN1 | THRB 2627/4885TSHR 840/4885ACHE 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.