Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PARL | Q9H300 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5977694 | 0.86 | MGLL (0.42) | KMT2AMGLLPSMB8PSMB5PARL | |
| SCHEMBL13997654 | 0.80 | NR4A2 (0.49) | KMT2AMGLLRAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL8597576 | 0.78 | ALDH1A1 (0.42) | KMT2AMGLLSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9258692 | 0.78 | PSMB8 (0.37) | KMT2AMGLLPSMB8PSMB5PARL | |
| SCHEMBL10720603 | 0.77 | L3MBTL1 (0.50) | KMT2AMGLLRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27463054 | 0.77 | MGLL (0.42) | KMT2AMGLLPSMB8PSMB5PARL | |
| SCHEMBL1781191 | 0.77 | KIF11 (0.41) | PSMB8PSMB5 | |
| SCHEMBL264659 | 0.76 | CYP2C19 (0.32) | PSMB8PSMB5POLB | |
| SCHEMBL43720 | 0.75 | TSHR (0.34) | MGLLPSMB8PSMB5 | |
| SCHEMBL9285468 | 0.75 | ALDH1A1 (0.34) | KMT2AMGLLPSMB8PSMB5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623028-A4 | NITROGEN-SULFUR LIGANDS AS OPIATE RECEPTOR MIMICS. | MALLINCKRODT MEDICAL INC (US) | 1995-03-29 | — | — | EP | disclosed |
| EP-0623028-A1 | NITROGEN-SULFUR LIGANDS AS OPIATE RECEPTOR MIMICS | MALLINCKRODT MEDICAL, INC. (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993010823-A1 | NITROGEN-SULFUR LIGANDS AS OPIATE RECEPTOR MIMICS | MALLINCKRODT MEDICAL, INC. (US) | 1993-06-10 | — | — | WO | disclosed |