SCHEMBL1781191

SCHEMBL1781191

O=C(CCSC(c1ccccc1)(c1ccccc1)c1ccccc1)ON1C(=O)CCC1=O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 18/20 0.41
SLC6A1 P30531 1/20 0.40
SLC6A11 P48066 1/20 0.40
PSMB8 P28062 1/20 0.37
PSMB5 P28074 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20081227 0.92 KIF11 (0.39) KIF11SLC6A1SLC6A11PSMB8PSMB5
SCHEMBL24311395 0.91 KIF11 (0.52) KIF11SLC6A1
SCHEMBL12603471 0.90 KIF11 (0.38) KIF11SLC6A1SLC6A11PSMB8PSMB5
SCHEMBL28736686 0.86 KIF11 (0.37) KIF11SLC6A1SLC6A11
SCHEMBL20081230 0.80 SLC6A1 (0.41) KIF11SLC6A1SLC6A11
SCHEMBL17488430 0.77 PSMB8 (0.32) PSMB8PSMB5
SCHEMBL9211737 0.77 KMT2A (0.42) PSMB8PSMB5
SCHEMBL9258692 0.77 PSMB8 (0.37) PSMB8PSMB5
SCHEMBL13523659 0.75 KIF11 (0.51) KIF11
SCHEMBL1534306 0.75 ALOX12 (0.56) KIF11SLC6A1SLC6A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF GENOSCO INC (US) 2026-04-23 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-20200206356-A1 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2020-07-02 US disclosed
US-20200121808-A1 SSTR-TARGETED CONJUGATES ENCAPSULATED IN PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2020-04-23 US disclosed
US-10624967-B2 Targeted conjugates and particles and formulations thereof TARVEDA THERAPEUTICS, INC. (US) 2020-04-21 US disclosed
US-20110117009-A1 DRUG CONJUGATES WITH POLYGLYCEROLS FREIE UNIVERSITÄT BERLIN (DE) 2011-05-19 US disclosed
WO-2009121564-A1 DRUG CONJUGATES WITH POLYGLYCEROLS FREIE UNIVERSITÄT BERLIN (DE) 2009-10-08 WO disclosed
US-20090035323-A1 IMMUNE RESPONSE MODIFIER CONJUGATES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2009-02-05 US disclosed
EP-1988896-A2 IMMUNE RESPONSE MODIFIER CONJUGATES 3M Innovative Properties Company (US) 2008-11-12 EP disclosed
WO-2007100634-A2 IMMUNE RESPONSE MODIFIER CONJUGATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-07 WO disclosed
EP-0856007-B1 CYCLOPEPTIDE DERIVATIVES MERCK PATENT GMBH (DE) 2004-04-21 EP disclosed
US-6566491-B2 Used as integrin inhibitors, in particular for the prevention and treatment of circulatory diseases, thrombosis, heart infarct, coronary heart diseases, arteriosclerosis, angiogenic diseases and in tumor therapy. MERCK PATENT GESELLSCHAFT (DE) 2003-05-20 US disclosed
US-20020032306-A1 CYCLOPEPTIDE DERIVATIVES BIOMET DEUTSCHLAND GMBH (DE) 2002-03-14 US disclosed
EP-0856007-A1 CYCLOPEPTIDE DERIVATIVES MERCK PATENT GmbH (DE) 1998-08-05 EP disclosed
WO-1997014716-A1 CYCLOPEPTIDE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1997-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109702-A1 NOVEL GSPT PROTEIN DEGRADER AND APPLICATION THEREOF CRBN, PSMB3, PSMB1 KIF11 4340/4885SLC6A1 3284/4885SLC6A11 3757/4885
US-20200121808-A1 SSTR-TARGETED CONJUGATES ENCAPSULATED IN PARTICLES AND FORMULATIONS THEREOF SSTR1, SSTR4, SSTR5 KIF11 1124/4885SLC6A1 903/4885SLC6A11 773/4885
US-10624967-B2 Targeted conjugates and particles and formulations thereof SSTR5, SSTR1, SSTR4 KIF11 988/4885SLC6A1 1239/4885SLC6A11 1214/4885
US-20200206356-A1 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR5, SSTR1, SSTR4 KIF11 988/4885SLC6A1 1239/4885SLC6A11 1214/4885
US-20110117009-A1 DRUG CONJUGATES WITH POLYGLYCEROLS DDOST, STT3A, STT3B KIF11 588/4885SLC6A1 2491/4885SLC6A11 1969/4885
US-20020032306-A1 CYCLOPEPTIDE DERIVATIVES CORO1C, CYCS, CORO1A KIF11 4588/4885SLC6A1 4569/4885SLC6A11 4483/4885
US-20090035323-A1 IMMUNE RESPONSE MODIFIER CONJUGATES IFNG, CD74, MYD88 KIF11 2020/4885SLC6A1 4758/4885SLC6A11 4652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.