Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9219585 | 0.99 | NR3C1 (0.50) | NR3C1NR3C2PDK1RORCRORA | |
| SCHEMBL9218206 | 0.84 | NR3C1 (0.44) | NR3C1NR3C2AR | |
| SCHEMBL9215571 | 0.80 | NR3C1 (0.49) | NR3C1NR3C2PDK1RORCRORA | |
| Hydrochloric Acid SCHEMBL9210683 | 0.79 | NR3C1 (0.48) | NR3C1NR3C2PDK1RORCRORA | |
| SCHEMBL1120903 | 0.79 | ADRA2C (0.51) | ADRA2CADRA1AADRA1BFABP4HTT | |
| SCHEMBL17170051 | 0.77 | ADRA2C (0.52) | ADRA2CADRA1AADRA1BFABP4HTT | |
| SCHEMBL9216909 | 0.75 | FABP4 (0.53) | ADRA2CADRA1AADRA1BFABP4 | |
| Hydrochloric Acid SCHEMBL9209804 | 0.75 | ADRA2C (0.57) | ADRA2CADRA1AADRA1BFABP4HTT | |
| SCHEMBL9214645 | 0.74 | NR3C1 (0.45) | NR3C1NR3C2ARRAB9A | |
| SCHEMBL9209192 | 0.72 | ALDH1A1 (0.53) | ADRA2CADRA1AADRA1BFABP4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538469-B1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 1995-09-27 | — | — | EP | disclosed |
| US-5360822-A | FOR TREATING URINARY INCONTINENCE IN ANIMALS AND HUMANS | NIPPON SHINYAKU CO. LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0538469-A1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-28 | — | — | EP | disclosed |