SCHEMBL921224

SCHEMBL921224

Nc1ncccc1C(=O)NCc1ccccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
MAPK8 P45983 4/20 0.65
KDM4E B2RXH2 2/20 0.57
PKM P14618 1/20 0.57
HSD17B10 Q99714 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.56
ALDH1A1 P00352 3/20 0.56
HPGD P15428 2/20 0.56
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C19 P33261 1/20 0.55
MAPK1 P28482 1/20 0.55
TDP1 Q9NUW8 1/20 0.54
TP53 P04637 1/20 0.53
RCE1 Q9Y256 1/20 0.53
PRKCI P41743 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL923290 0.84 MAPK8 (0.53) MEN1KMT2AMAPK8ALDH1A1HPGD
SCHEMBL922837 0.84 HPGD (0.68) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL921483 0.84 LMNA (0.66) MEN1KMT2AMAPK8KDM4EALDH1A1
SCHEMBL922034 0.82 PRKCI (0.53) MEN1KMT2AMAPK8KDM4EL3MBTL1
SCHEMBL29994178 0.81 ALDH1A1 (0.68) MEN1KMT2AMAPK8KDM4EHSD17B10
SCHEMBL14727425 0.81 ALDH1A1 (0.68) MEN1KMT2AMAPK8KDM4EHSD17B10
SCHEMBL922492 0.80 NSD2 (0.66) KMT2AMAPK8L3MBTL1HPGDMAPK1
SCHEMBL14426745 0.80 MEN1 (0.76) MEN1KMT2AMAPK8KDM4EPKM
SCHEMBL921031 0.78 KLKB1 (0.49) MEN1KMT2AMAPK8KDM4EALDH1A1
SCHEMBL919882 0.78 MAPK14 (0.61) KMT2AMAPK8L3MBTL1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MEN1 4723/4885KMT2A 2469/4885MAPK8 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.