SCHEMBL921483

SCHEMBL921483

Nc1ncccc1C(=O)NCc1ccccc1F

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.66
MAPK8 P45983 1/20 0.54
ROCK1 Q13464 1/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
PRKCI P41743 2/20 0.52
HPGD P15428 4/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 1/20 0.52
TSHR P16473 1/20 0.52
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47
KDM4E B2RXH2 1/20 0.47
NAPRT Q6XQN6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920094 0.85 PRKCI (0.50) LMNAMAPK8ROCK1MEN1KMT2A
SCHEMBL1681097 0.85 LMNA (0.50) LMNAMAPK8ROCK1MEN1KMT2A
SCHEMBL1681273 0.84 SCN3A (0.56) LMNAMAPK8MEN1KMT2ANPC1
SCHEMBL921224 0.84 MEN1 (0.67) MAPK8MEN1KMT2ANPC1RAB9A
SCHEMBL922837 0.84 HPGD (0.68) LMNAMEN1KMT2APRKCIHPGD
SCHEMBL921031 0.83 KLKB1 (0.49) LMNAMAPK8ROCK1MEN1KMT2A
SCHEMBL922034 0.82 PRKCI (0.53) LMNAMAPK8MEN1KMT2APRKCI
SCHEMBL921573 0.81 MAPK8 (0.53) LMNAMAPK8PRKCIALDH1A1
SCHEMBL923356 0.81 KMT2A (0.49) LMNAMAPK8MEN1KMT2ANPC1
SCHEMBL31424194 0.81 HPGD (0.68) LMNAROCK1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 LMNA 4812/4885MAPK8 2313/4885ROCK1 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.