Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207091 | 0.79 | DDAH1 (0.37) | TP53FAAH | |
| SCHEMBL7992191 | 0.74 | TP53 (0.51) | SHMT2LMNAPOLBACACBTHRB | |
| SCHEMBL219441 | 0.72 | POLB (0.48) | SHMT2LMNAPOLBTHRBFAAH | |
| SCHEMBL3407130 | 0.70 | SHMT2 (0.56) | SHMT2LMNAPOLBSOAT1THRB | |
| SCHEMBL9209032 | 0.69 | SOAT1 (0.46) | SHMT2LMNAPOLBSOAT1ACACB | |
| SCHEMBL6211191 | 0.69 | SOAT1 (0.57) | SOAT1 | |
| SCHEMBL6213768 | 0.69 | SOAT1 (0.75) | SOAT1 | |
| SCHEMBL6211076 | 0.69 | SOAT1 (0.75) | SOAT1 | |
| SCHEMBL4758192 | 0.69 | POLB (0.46) | SHMT2LMNAPOLBTHRBTP53 | |
| SCHEMBL9210293 | 0.68 | LMNA (0.65) | SHMT2LMNAPOLBTHRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0405976-A1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-02 | — | — | EP | disclosed |