Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218534 | 0.86 | SRC (0.47) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9219234 | 0.83 | NPC1 (0.57) | EGLN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9221803 | 0.83 | ALDH1A1 (0.44) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9213350 | 0.82 | RAB9A (0.52) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9172768 | 0.82 | RAB9A (0.55) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9220312 | 0.82 | RAB9A (0.39) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9214289 | 0.80 | KDR (0.50) | EGLN2ALDH1A1FYNCYP1A2CYP3A4 | |
| SCHEMBL9216208 | 0.80 | SMN1; SMN2 (0.40) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9212121 | 0.79 | KDR (0.44) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9222661 | 0.79 | SIGMAR1 (0.40) | NPC1RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269859-B2 | Pyrazolotriazine compounds | OTSUKA PHARMA CO LTD (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-4824834-A | TREATING GOUT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0269859-A2 | Pyrazolotriazine compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |