SCHEMBL921436

SCHEMBL921436

Cc1ccc(C)c(Oc2ccc(CNC(=O)c3cccnc3N)cc2)c1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.50
LMNA P02545 2/20 0.50
POLB P06746 2/20 0.50
MAPK8 P45983 1/20 0.48
MAPK14 Q16539 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920225 0.92 LIPG (0.52) HPGDSMN1; SMN2LMNAPOLBMAPK8
SCHEMBL919966 0.89 MAPK14 (0.61) HPGDSMN1; SMN2LMNAPOLBMAPK8
SCHEMBL922484 0.88 HPGD (0.62) HPGDSMN1; SMN2LMNAPOLBMAPK8
SCHEMBL920949 0.87 MAPK8 (0.50) HPGDSMN1; SMN2LMNAPOLBMAPK8
SCHEMBL921056 0.86 LMNA (0.57) HPGDSMN1; SMN2LMNAPOLBMAPK8
SCHEMBL920714 0.85 MAPK8 (0.53) HPGDSMN1; SMN2LMNAPOLBMAPK8
SCHEMBL921006 0.85 HPGD (0.51) HPGDSMN1; SMN2LMNAPOLBMAPK8
SCHEMBL922349 0.85 HPGD (0.53) HPGDSMN1; SMN2LMNAPOLBMAPK8
SCHEMBL921191 0.83 MAPK8 (0.50) HPGDSMN1; SMN2LMNAPOLBMAPK8
SCHEMBL920122 0.83 HPGD (0.68) HPGDSMN1; SMN2LMNAPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885SMN1; SMN2 4796/4885LMNA 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.