SCHEMBL921316

SCHEMBL921316

Cc1ccc(Oc2ccc(CNC(=O)c3ccc(F)nc3N)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 3/20 0.53
MMP13 P45452 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CYP3A4 P08684 2/20 0.52
HTT P42858 2/20 0.52
MMP2 P08253 1/20 0.52
STAT3 P40763 1/20 0.52
HPGD P15428 4/20 0.50
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 1/20 0.50
LIPG Q9Y5X9 1/20 0.47
PTGER4 P35408 1/20 0.46
CHRNA7 P36544 1/20 0.45
MAPT P10636 3/20 0.45
RXFP1 Q9HBX9 2/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920140 0.91 EGLN1 (0.51) SMN1; SMN2HPGDALDH1A1LIPGMAPT
SCHEMBL921095 0.91 LIPG (0.47) MAPK14MMP13SMN1; SMN2CYP3A4HTT
SCHEMBL920506 0.91 CYP3A4 (0.54) MAPK14SMN1; SMN2CYP3A4HTTLIPG
SCHEMBL921469 0.89 MAPK14 (0.52) MAPK14MMP13SMN1; SMN2CYP3A4HTT
SCHEMBL922765 0.89 MAPK14 (0.47) MAPK14MMP13SMN1; SMN2CYP3A4HTT
SCHEMBL920433 0.89 MMP13 (0.56) MAPK14MMP13SMN1; SMN2CYP3A4HTT
SCHEMBL919844 0.89 LIPG (0.45) MAPK14MMP13SMN1; SMN2CYP3A4HTT
SCHEMBL921032 0.89 POLB (0.51) SMN1; SMN2HPGDKDM4ELIPGRXFP1
SCHEMBL920472 0.88 LIPG (0.44) MAPK14MMP13SMN1; SMN2CYP3A4HTT
SCHEMBL921215 0.88 AKR1B1 (0.44) MAPK14CYP3A4HPGDALDH1A1LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK14 905/4885MMP13 4062/4885SMN1; SMN2 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.