Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211998 | 0.91 | ALDH1A1 (0.38) | ALDH1A1PKMHTTTSHRNAMPT | |
| SCHEMBL9219652 | 0.91 | ALDH1A1 (0.38) | ALDH1A1PKMHTTTSHRNAMPT | |
| SCHEMBL9211109 | 0.90 | MEN1 (0.37) | ALDH1A1HTTTSHRNAMPTMEN1 | |
| SCHEMBL9219765 | 0.90 | ALDH1A1 (0.39) | ALDH1A1NAMPTMEN1KMT2ATBXAS1 | |
| SCHEMBL9217629 | 0.90 | SLC1A3 (0.36) | ALDH1A1PKMHTTTSHRNAMPT | |
| SCHEMBL9218839 | 0.88 | KMT2A (0.36) | ALDH1A1MMP1MMP2MMP3MMP7 | |
| SCHEMBL9216670 | 0.87 | P2RX7 (0.33) | ALDH1A1SLC6A4MEN1KMT2A | |
| SCHEMBL9209313 | 0.86 | NAMPT (0.33) | ALDH1A1HTTTSHRNAMPTMEN1 | |
| SCHEMBL9211995 | 0.84 | GRIA2 (0.32) | ALDH1A1SLC6A4KCNH2 | |
| SCHEMBL9216847 | 0.82 | TSHR (0.38) | ALDH1A1PKMHTTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |