Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211998 | 0.92 | ALDH1A1 (0.38) | ALDH1A1GAAPTGS2MEN1KMT2A | |
| SCHEMBL9219652 | 0.92 | ALDH1A1 (0.38) | ALDH1A1GAAPTGS2MEN1KMT2A | |
| SCHEMBL9211109 | 0.91 | MEN1 (0.37) | ALDH1A1GAAPTGS2MEN1KMT2A | |
| SCHEMBL9217629 | 0.91 | SLC1A3 (0.36) | ALDH1A1MEN1KMT2AS1PR1NAMPT | |
| SCHEMBL9215115 | 0.90 | KEAP1 (0.39) | ALDH1A1MEN1KMT2ATBXAS1NAMPT | |
| SCHEMBL9218839 | 0.89 | KMT2A (0.36) | ALDH1A1GAAMEN1KMT2ATBXAS1 | |
| SCHEMBL9209313 | 0.89 | NAMPT (0.33) | ALDH1A1MEN1KMT2AHSD11B1NAMPT | |
| SCHEMBL9216670 | 0.88 | P2RX7 (0.33) | ALDH1A1GAAPTGS1PTGS2MEN1 | |
| SCHEMBL9211995 | 0.86 | GRIA2 (0.32) | ALDH1A1GAA | |
| SCHEMBL9216847 | 0.84 | TSHR (0.38) | ALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |