Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216670 | 0.87 | P2RX7 (0.33) | GAAALDH1A1KMT2A | |
| SCHEMBL9217629 | 0.87 | SLC1A3 (0.36) | TSHRALDH1A1PKMHTTKMT2A | |
| SCHEMBL9219652 | 0.86 | ALDH1A1 (0.38) | TSHRGAAALDH1A1PKMMAPT | |
| SCHEMBL9211998 | 0.86 | ALDH1A1 (0.38) | TSHRGAAALDH1A1PKMMAPT | |
| SCHEMBL9211995 | 0.85 | GRIA2 (0.32) | GAAALDH1A1 | |
| SCHEMBL9211109 | 0.84 | MEN1 (0.37) | TSHRKDM4EGAAALDH1A1MAPT | |
| SCHEMBL9219765 | 0.84 | ALDH1A1 (0.39) | GAAALDH1A1KMT2A | |
| SCHEMBL9214348 | 0.83 | GAA (0.33) | GAAALDH1A1MAPTKMT2A | |
| SCHEMBL9210074 | 0.83 | PKM (0.32) | ALDH1A1PKMKMT2A | |
| SCHEMBL9215115 | 0.82 | KEAP1 (0.39) | TSHRKDM4EALDH1A1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-B1 | THIOFORMAMIDE DERIVATIVES | RHONE POULENC RORER SA (FR) | 1995-03-15 | — | — | EP | claimed |